1. Treatment of Graves' Disease with Antithyroid Drugs.
نویسندگان
چکیده
منابع مشابه
Treatment of hyperthyroidism with antithyroid drugs corrects mild neutropenia in Graves' disease.
CONTEXT Neutropenia secondary to antithyroid drug (ATD) therapy in Graves' disease (GD) is well recognized. However, the effect of hyperthyroidism, prior to and after ATD therapy, on neutrophil counts in patients with GD is unclear. OBJECTIVE To study the prevalence of neutropenia in newly diagnosed untreated GD and the effect of ATD on the neutrophil count. DESIGN Prospective study from Au...
متن کاملPrognostic Factors in the Relapse of Graves’ Disease Following Treatment with Antithy-roid Drugs
Background: Patients with Graves’ disease exhibit a considerable rate of relapse after treatment with antithyroid drugs and require ablative therapy. Objective: The purpose of this study was to evaluate variables which can be used as prognostic factors in predicting the outcome of Graves’ disease after treatment with antithyroid drugs. Methods: Age, sex, duration of antithyroid drug therapy, pr...
متن کاملRelationship between dose of antithyroid drugs and adverse events in pediatric patients with Graves’ disease
Graves' disease (GD) accounts for a large proportion of pediatric hyperthyroidism, and the first-line treatment is antithyroid drug (ATD) therapy. Methimazole (MMI) is effective in most patients but is associated with significant adverse events (AEs). We reviewed the medical records of GD patients (n = 56) with onset age of <15 yr and investigated the relationship between MMI dose and AEs. The ...
متن کاملTreatment of graves' disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation.
BACKGROUND Several reports have suggested that propylthiouracil (PTU) may be safer than methimazole (MMI) for treating thyrotoxicosis during pregnancy because congenital malformations have been associated with the use of MMI during pregnancy. OBJECTIVES We investigated whether in utero exposure to antithyroid drugs resulted in a higher rate of major malformations than among the infants born t...
متن کاملAntithyroid Drugs
The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2010
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.99.733